Search results for "Acute retinal necrosis"

showing 2 items of 2 documents

Kyrieleis´ vasculitis in acute retinal necrosis

2010

Ester Francés-Muñoz1, Roberto Gallego-Pinazo1, Ruth López-Lizcano1, Salvador García-Delpech1, J Luis Mullor3, Manuel Díaz-Llopis1,21Department of Ophthalmology, Hospital La Fe, Valencia, Spain; 2University of Valencia, Valencia, Spain; 3Unit of Experimental Ophthalmology. Fundación para la Investigación del Hospital Universitario La Fe. Valencia, Valencia, SpainAbstract: We report the first case in the literature of Kyrieleis´ vasculitis related to acute retinal necrosis by Varicella zoster virus in a 76-year-old woman with bilateral involvement. In our patient the arterial lesions appeared 15 days after …

Pathologymedicine.medical_specialtyRetinal necrosisintegumentary systembusiness.industryvirusesVaricella zoster virusvirus diseasesClinical Ophthalmologymedicine.diseasemedicine.disease_causeOphthalmologyHerpes virusmedicineAcute retinal necrosisPresentation (obstetrics)VasculitisbusinessClinical Ophthalmology
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Liposomally-entrapped ganciclovir for the treatment of cytomegalovirus retinitis in AIDS patients

1992

Treatment of retinitis by cytomegalovirus (CMV) in AIDS patients requires frequent repetitive injections of intravitreal ganciclovir (GCV). This study was undertaken to establish experimentally whether the intravitreal application of liposomally-entrapped GCV could prolong intraocular therapeutic levels when compared with the intravitreal injection of free GCV, and the clinical effectiveness of this approach in AIDS patients. Intraocular concentration of GCV was determined by means of an ELISA test in rabbit vitreous 2, 3, 7, and 14 days after a single intravitreal injection of either different doses of the free drug (0.2-20 mg) or 1 mg of liposomally-entrapped GCV. After 72 h, only the vit…

Ganciclovirvirusesmedicine.medical_treatmentEye Infections ViralRetinitisPharmacologyRetinaPharmacokineticsBetaherpesvirinaePhysiology (medical)medicineAnimalsHumansGanciclovirDrug CarriersChemotherapyAIDS-Related Opportunistic Infectionsbiologybusiness.industryRetinitisRetinitebiology.organism_classificationmedicine.diseaseSensory SystemsOphthalmologyTreatment OutcomeCytomegalovirus InfectionsLiposomesRabbitsAcute retinal necrosisCytomegalovirus retinitisbusinessFollow-Up Studiesmedicine.drugDocumenta Ophthalmologica
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